I just looked and Time Crisis 5 is not even in Teknoparrot, even if it was there would be zero reason to use it. If you're referring to another game this thread is only for Time Crisis 5 use the Teknoparrot thread. Also why isn't your game fullscreen anyway? I never had a problem with that so I can't help you there but I can tell you the rest. Download the zip for nomousy extract it and put it in the director of TimeCrisisGame-Win64-Shipping, this script with nomousy will make the mouse cursor disappear and reappear when hitting escape. I don't know if you're using Demulshooter I also put the Demulshooter files in the same directory so I don't have to add any paths.
#NoEnv ; Recommended for performance and compatibility with future AutoHotkey releases.
; #Warn ; Enable warnings to assist with detecting common errors.
SendMode Input ; Recommended for new scripts due to its superior speed and reliability.
SetWorkingDir %A_ScriptDir% ; Ensures a consistent starting directory.
#SingleInstance, force
Run, DemulshooterX64.exe -target=es3 -rom=tc5
Run, nomousy.bat
run, "TimeCrisisGame-Win64-Shipping.exe" -NOINI -Language=JPN -playside=1
MButton::t
RButton::y
5::<+t
1::<+h
Escape::
Process,Close,TimeCrisisGame-Win64-Shipping.exe
Run,taskkill /im "TimeCrisisGame-Win64-Shipping.exe" /F
Run nomousy.exe
ExitApp
return
nomousy.zip